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Mitotane also known as o p DDDLysodren is an antineoplastic medication used in the treatment of adrenocortical carcinoma. It has a molecular weight of 320. When cortisol levels get too low low blood pressure, it can cause a variety of symptoms, such as muscle weakness, weight loss, fatigue which may be life threatening. Inactive ingredients in.

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Prepared with input from the Cancer Lysodren 500 mg tablets Summary of Product CharacteristicsSPC) Mitotane reduced basal CORT levels to nondetectable and abol- ished stress induced CORT increases by the 3rd day of treatment. Acute side effects include loss of appetite itch, nausea , vomiting, allergic reactionskin rash, redness low.

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Take mitotane at around the same times every day. 4b) that for the androstenedione metabolites androsterone5α reduced) aetiocholanolone5β reduced the degree of decrease in 5α reduction was not as profound as for cortisol.

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